Environmental stressors and the epigenome.
نویسندگان
چکیده
Epigenetic modification and transgenerational transfer of phenotype at the individual or population level, particularly in response to environmental change, is at the forefront of biological investigation. The plasticity of this process allows an organism to respond to changes in environmental conditions, potentially conferring a survival advantage. In this review, we discuss epigenetic transgenerational phenomena in the specific context of environmental stressors including hypoxia and environmental toxicants.:
منابع مشابه
Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk
Recent advances in laboratory sciences hold a promise for a ‘leap forward’ in understanding the aetiology of complex human diseases, notably cancer, potentially providing an evidence base for prevention. For example, remarkable advances in epigenomics have an important impact on our understanding of biological phenomena and importance of environmental stressors in complex diseases. Environmenta...
متن کاملCharacterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk
Recent advances in laboratory sciences hold a promise for a ‘leap forward’ in understanding the aetiology of complex human diseases, notably cancer, potentially providing an evidence base for prevention. For example, remarkable advances in epigenomics have an important impact on our understanding of biological phenomena and importance of environmental stressors in complex diseases. Environmenta...
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متن کاملCharacterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk.
Recent advances in laboratory sciences hold a promise for a 'leap forward' in understanding the aetiology of complex human diseases, notably cancer, potentially providing an evidence base for prevention. For example, remarkable advances in epigenomics have an important impact on our understanding of biological phenomena and importance of environmental stressors in complex diseases. Environmenta...
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ورودعنوان ژورنال:
- Drug discovery today. Technologies
دوره 12 شماره
صفحات -
تاریخ انتشار 2014